Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep284 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Inflammasome components and food addiction behaviors in morbid obesity and bariatric surgery: Novel promising targets for a chronic disease

Herrero-Aguayo Vicente , Sáez-Martínez Prudencio , Luis López-Cánovas Juan , Jesús Montero-Hidalgo Antonio , Membrives Antonio , David Gahete Manuel , José Molina-Puerta María , Pastor Castaño Justo , Ángeles Gálvez-Moreno María , Miguel Luque Raúl , Dulcinea Herrera-Martínez Aura

Obesity is a chronic metabolic disease associated with important metabolic and inflammatory comorbidities, which can be reversed or improved after bariatric-surgery (BS). However, some underlying mechanisms, independent of weight-loss, are still unknown. In this context, dysregulations in the inflammasome, a multiproteic complex that promotes cytokine maturation and induces cellular pyroptosis, has been associated to the development/stage of some cancer-types and obesity. Howe...